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These include oxidative inactivation of antiproteinases, airspace epithelial injury, increased sequestration of neutrophils in the pulmonary microvasculature, and gene expression of proinflammatory mediators

A preclinical safety evaluation published in ScienceDirect confirmed that BPC-157 showed no test-related toxicity in single-dose and repeated-dose studies across mice, rats, rabbits, and dogs, with no genetic or embryo-fetal toxicity detected

Furthermore, we demonstrate for the first time that in CSF of MS patients, the Fe 2+ /Fe 3+ ratios are elevated compared to non-MS controls

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