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Among the key causative agents, anthracyclines, such as doxorubicin (DOX), are particularly notable, as the severe cardiac damage they inducecharacterized by ventricular dilatation, interstitial fibrosis, and progression to HFsignificantly limits their clinical utility [73]

The rationale behind this blend draws from emerging research on cagrilintide and retatrutide co-administration

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Peer review Peer review information Nature Reviews Drug Discovery thanks Michael Nauck, Stefan Trapp and the other, anonymous, reviewer(s) for their contribution to the peer review of this work