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Sigma-Aldrich #E8655), BCL-2 (anti-rabbit, 1:2000, abcam ab182858), BAX (anti-rabbit, 1:2000, abcam ab182733) overnight

Implications & Mechanisms The fact that Reta slowed tumor growth without causing weight loss suggests it may act through: Direct effects on tumor cells and/or Modulation of immune responses or metabolism inside the tumor microenvironment

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They support mitochondrial ATP production in brain cells, replenish dopamine and norepinephrine (the neurotransmitters most responsible for drive and motivation), and regulate the stress hormones that drain mental stamina