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Yusuf N, Irby C, Katiyar SK, et al

Enhancements in neuronal homeostasis resulting from microglial depletion included the mitigation of post-TBI dendritic complexity, inhibition of most post-TBI transcriptional changes, interruption of neuronal connectivity and plasticity alongside functional deficits, and the mitigation of post-TBI cognitive impairments

However, most published sermorelin trials are short-term (412 weeks) and small in sample size

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