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The 1 H-NMR spectra showed the disappearance of the doublet signals corresponding to the -lactam ring protons (H5 and H6) of AX at 5.39 and 5.35 ppm (J 5,6 = 3.9 Hz), and their appearance at 4.02 and 5.17 ppm (J 5,6 = 2.6 Hz) ( Figure 2C )