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These might be injuries directly to the muscle or various muscle disabilities deriving from a multitude of causes, peripheral and/or central (for review, see [1,7,8,9])

Another indication is persistent extraesophageal symptoms despite high-dose PPI therapy in patients with confirmed reflux disease

Another important direction is the characterization of doseresponse relationships, pharmacokinetics, and tissue-specific bioavailability of AX, especially in skeletal muscle under metabolic stress

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