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In acute animal injury models, repair cascade activation is relatively rapid

Loop structure, with which AMPs often contain an intramolecular disulfide bond at the C-terminus to form a loop, while the N-terminus is a linear structure, forming a cyclic chain structure, such as bovine neutrophils-derived AMP (bactenecin) 58 and frog skin-derived AMP (brevinins)

Russell AL, Kennedy AM, Spuches AM, Gibson WS, Venugopal D, Klapper D, Srouji AH, Bhonsle JB, Hicks RP (2011) Determining the effect of the incorporation of unnatural amino acids into antimicrobial peptides on the interactions with zwitterionic and anionic membrane model systems