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GLXI isomerizes the hemithioacetal (HTA) formed by the spontaneous reaction between GSH and MG, into S-D-lactoylglutathione

Mice treatment with AZT did not exhibit a significant decrease in GSH in total muscle homogenate, but the GSSG concentration increases, leading an increase in GSSG/GSH ratio

2.4 Modulation of the tumor microenvironment The cellular environment in which tumors exist is referred to as TME, which comprises stromal cells, immune cells, and extracellular components and plays an essential role in tumor progression, drug resistance, and immune escape ( Figure 4 )

A longitudinal skin incision and passive separation of connective tissue and fat tissue were made to expose the femoral vessels