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34,87 PGC-1 increases expression of carnitine palmitoyltransferase 1A and acyl-CoA oxidase 1, supporting fatty acid transport and oxidation within mitochondria and reducing hepatic lipid droplet accumulation

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Although the APAP toxicity-associated acute liver failure has better outcome than other causes of liver failure, mortality is still significant in 30% of cases without a liver transplant (for those who are deemed in need of a transplant)

Treatment may be paused or adjusted if serious issues arise