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This controversial view was not universally accepted, and it is likely that the peculiar geographical and global circumstances of the day conspired to generate a unique population-level experiment

When it loses integrity, the barrier becomes more permeable and that increased permeability is precisely what leaky gut is meant to describe

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But if your goal, as is the case in most dedicated research, is to explore the absolute maximum potential for tissue regeneration and recovery, the evidence strongly suggests that these two should be kept far apart