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Morsi 3 , Tareq Kass-Hout 3 , Tanya Turan 1 1 Medical University of South Carolina, Charleston, United States, 2 Emory University Hospital, Atlanta, United States, 3 University of Chicago, Chicago, United States Background and Aims: Limited data exist on the optimal antithrombotic regimen for atrial fibrillation (AF) patients with acute stroke caused by intracranial (sICAS) or extracranial (sECAS) atherosclerosis

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Under oxidative stress, the transcription factor Nrf2 (Nuclear Factor Erythroid 2-Related Factor 2) translocates from the cytoplasm into the nucleus and binds to the antioxidant response element (ARE)