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In addition to the TLR7 agonist-loaded nanoparticles that can polarize M2 TAMs to M1 TAMs, liposomal R848-LPs loaded with the TLR-7/8 agonist resiquimod (R848) can also rapidly accumulate at tumor sites and R848-targeting TAMs can polarize TAMs to type M1, and this nanoparticle can also enhance the anti-tumor effect of therapeutic antibodies by enhancing antibody-dependent cell phagocytosis (ADCP) effects (40)

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In Ddit4 fl/fl mice, direct donation of mitochondrial membrane to form autophagosomes (Fig

It originated from research involving protective compounds associated with the stomach and gastrointestinal tract