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Bioaccumulation and biomagnification Non-biodegradable NPs can accumulate in species bodies, causing biomagnification in the food chain as shown in Fig

The reduced expression of pykF in MG12345 led to an increase in the intracellular concentration of PEP and also caused an increase in the concentrations of G6P and F6P, which in turn decreased the glucose uptake rate

Furthermore, elevated uric acid observed in SCC47 compared to Detroit562 indicates active purine catabolism, suggesting differences in proliferation rates or preferential recycling of purines back to guanosine monophosphate (GMP) and inosine monophosphate (IMP) 32

Using a combination of targeted nutrients can create a more resilient system