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IGF1 interacts with Testosterone and AR receptors, studies show that IGF1 can directly stimulate testosterone production by testicular interstitial cells

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When evaluating diagnostic properties of DPS p-tau217, we assessed cutoffs derived with 90% sensitivity, 90% specificity or maximum Youdens Index for CSF or venous plasma biomarker positivity and computed their respective NPV and PPV based on the prevalence of biomarker positivity in the subset of participants with available data for each analysis

Peripheral whole blood was collected in the perioperative setting via a venous catheter immediately before surgery using K 2 -EDTA-coated tubes (BD Biosciences, 367899)