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For individuals requiring supplementation due to confirmed deficiency or malabsorption, therapeutic doses vary considerably depending on the underlying cause: Dietary deficiency : 50150 micrograms daily orally, or cyanocobalamin tablets as prescribed Pernicious anaemia : Initially hydroxocobalamin 1 mg intramuscularly three times weekly for two weeks, then maintenance injections every two to three months [3] Neurological involvement : More intensive regimens may be required, with hydroxocobalamin injections on alternate days until symptom improvement [3] NICE guidance emphasises that supplementation should be evidence-based rather than speculative

30 mL) and is intended for intramuscular or intravenous administration by healthcare professionals

However, if you are unsure or lack experience, it is always best to seek assistance from a healthcare professional or someone experienced in giving intramuscular injections to ensure proper and safe administration

J., Kim, J