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Thus, promoting fibrosis in IVD may offer a method for tissue repair and for helping stabilize the spine

Int J Chron Obstruct Pulmon Dis (2008) 3(2):25368

[3] This is a fundamentally different problem from that faced by single-agonist drugs, and it is why the class is sometimes described as polypharmacology in one molecule. A useful way to picture the balance problem is to imagine two dials on the same molecule