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Sm KI-1 is accompanied in the tegument by Sm 200, a 200 kDa protein used for diagnostic purposes, but whose only characterized function to date is the causation of an increased abundance in IL-10 secretion from surrounding cells (154)

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similarly, while the niacinamide in this compounded B-Complex is in a moderate dose, caution is advised in patients with untreated peptic ulcers or significant hepatic impairment, as even moderate niacin supplementation could aggravate these conditions (e.g