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Several rodent studies link BPC-157 to the VEGF-receptor-2 / Akt / endothelial nitric oxide synthase (eNOS) signaling axis, which would connect its reported angiogenic and vasodilatory effects to a single upstream pathway

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One week after the conditioning procedure, treatment was started and continued daily for two months, when mice were tested for behavioral performance, euthanized and brains collected for neuropathology

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