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These data, together with the three published clinical trials with negative results, do not support treatment with uric acid-lowering drugs in patients with CKD to reduce progression of renal function deterioration

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LEGENDplex Assay (Biolegend) was performed using 20 g protein and 20 l supernatant in a LEGENDplex HU Th Cytokine Panel (BioLegend)