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Successful use of LT4 is facilitated by multiple factors including experience with its efficacy in resolving the symptoms of hypothyroidism, long-term experience of its benefits, a favorable side effect profile, ease of administration, good intestinal absorption, a long serum half-life, the stable T3 levels that are produced, and its low cost (1)

As a result, it is one of the most popular dietary supplements for supporting weight management and enhancing athletic performance

The integration of AI and omics has also propelled advances in network pharmacology