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The cytosolic CHAC proteins have a GCT-fold, which places them within the GCT protein family (Kumar et al., 2012

These inves-tigators are experimenting with a regimen of NAC 150 mg/kg in dextrose 5% infused intravenously over 30 minutes followed by 15 mg/kg/h for 4 days as an antioxidant active radical scavenger

Protease-sensitive cleavable linkers use the dominant proteases found in tumor cell lysosomes for recognition and cleavage of a specific peptide sequence in the linker