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Furthermore, MSCs can induce the transformation of mature dendritic cells into immunosuppressive regulatory dendritic cells via jagged-2 and IL-10-activated SOCS3 pathways while escaping from their apoptotic fate (145, 146), and IL-10-plasmacytoid dendritic cells (pDCs) can be induced by PGE2 (124)

Mitochondrial fission and calcium overload are closely interconnected, influencing each other and significantly impacting cellular homeostasis and pathology

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