While the implications for SARM1 in regulating axonal fate are well-established, the sensing mechanisms of this protein complex toward NAD + , NMN, or even possibly toward other NAD + metabolites are not fully understood, and may suggest that also the other NAD + metabolites could regulate more biological processes than initially thought 54
Cancer Res Summary Keywords glutathione S -conjugate, prodrug, cancer, drug resistance, glutathione transferase, gamma-glutamyl transferase Citation Ramsay EE and Dilda PJ (2014) Glutathione S -conjugates as prodrugs to target drug-resistant tumors
473,474,475,476,477 -Adrenergic drugs such as guanfacine are used for ADHD and disruptive behaviour
These numbers reflect reported experimental parameters only and are shared strictly for research use, never as guidance for human use