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After obtaining favorable results in the investigator-initiated Phase III trial JETALS, and following consultation with Tokushima University, Eisai submitted a new drug application for the treatment of ALS in Japan in January 2024, leading to its approval in September, 2024 and leading to the launch today

Haematological malignancies: Myeloproliferative disorders (polycythaemia vera, chronic myeloid leukaemia) and some lymphomas increase B12-binding proteins, particularly haptocorrin, raising measured serum levels

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