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10.1007/s11689-011-9081-8 J

Clinically, healthcare providers must adopt proactive pharmacovigilance strategies, including regular neurological assessments, patient education on early symptoms, and interprofessional collaboration in drug management

Notably, PGRMC1 also binds other cytochrome P450 enzymes, such as cytochrome P450 family 3 subfamily A member 4 (CYP3A4), suggesting that individual variability in PGRMC1 function may influence broader drug metabolism pathways [49]

These methods yield higher-quality genome assemblies, which reveal both the evolutionary history and functional attributes of the genome [263]