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However, it is important to note that, despite substantial evidence supporting the role of complement opsonization in MSU-induced immune activation, systematic data on the quantitative composition, spatial organization, and temporal dynamics of specific lectins, immunoglobulins, and other opsonic proteins within the crystal-associated coating layer are still limited

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Avoid stimulants like coffee, tea, and alcohol, as these can aggravate Rosacea and cause heat and blood stimulation to the area making symptoms worse