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GLUT4, which is primarily located in striated muscle (skeletal and cardiac) and adipose tissue, plays a major role in regulating glucose uptake and overall energy balance

Author Contributions Conceived and designed the experiments: PJ HCM AVP SM YL YHC NAB EW

Moreover, in these sporadic cases of severe G6PD deficiency with CGD, PPP flux is markedly diminished to the point of impaired NADPH oxidase activity and absent NETosis (28), and the impaired phagocytic respiratory burst was clinically linked to cases of mycobacterial infection (29)