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Another proposed mechanism involves the binding of homocysteine to the collagenous matrix of bone, which may modify collagen properties and reduce bone strength (reviewed in 113)

Particularly among the elderly, those with untreated hearing loss are less likely to participate in social activities and more likely to report levels of depression and anxiety (Bess et al., The primary cellular basis for ototoxic hearing loss is the death of sensory hair cells within the cochlea

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BPC-157 is not FDA-approved for human therapeutic use and is classified as a Category 2 bulk drug substance by the FDA