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that in both the probiotic and placebo groups there were shifts in both microbiota composition and resistome incurred by antibiotic treatment that were specific, reproducible and predictable for a number of bacterial families and ABR classes/genes for both groups 6

A clustering of contamination events or persistent post-inflammatory hyperpigmentation cases tied to specific at-home protocols would shift the recommendation toward more conservative cadence or stricter contraindication screening

doi: 10.1152/ajpendo.00308.2007

A dented crimp, a cracked vial, or a stopper displaced from its seated position compromises sterility regardless of the product's chemical stability