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As a result, cellular pro-inflammatory responses are suppressed, which inhibits formation of DNA adducts and reduces the mutation rate [84]

First, SFN stands as a exemplary multi-targeted agent whose pleiotropic mechanismsspanning epigenetic regulation, induction of specialized cell death programs, immunomodulation, and CSC targetingprovide a robust foundation for its efficacy against heterogeneous and treatment-resistant malignancies

In AD, keratinocytes exhibit impaired differentiation, increased apoptosis, and dysfunctional lipid production, leading to a compromised skin barrier that permits allergen entry and moisture loss

Balanced nutrition, mindful sunlight exposure, healthy gut function, and stress management support long-term prevention