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Further elucidation of these mechanisms may enhance our understanding of pyroptosis in DOR and aid in the development of natural product-based therapies targeting pyroptosis-related factors

Itaconate also dampens NLRP3 activity after prolonged LPS exposure, playing an important role in the resolution of inflammation [117], and suppression of itaconate can contribute to chronic inflammation

Unlike full-length HGH, AOD-9604 has been studied for its ability to selectively influence fat metabolism without affecting blood sugar or cell proliferation markers

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