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Cell Death Dis 5(10):e1442 Pearson-Smith JN, Patel M (2017) Metabolic dysfunction and oxidative stress in epilepsy [J]

In early DN, ATP-binding cassette A1 (ABCA1) loss caused damage to glomerular endothelial cells through endoplasmic reticulum stress (ERS)-induced inflammation and apoptosis, which finally resulted in DN progression (118)

Two weeks after stroke, immature, DCX + GCs showed an accelerated maturation of passive properties such as a lower input resistance, resting potential and membrane time constant, and were more likely to fire fast, brief action potentials characteristic of mature neurons (Figure 2C, last panel)

The combination of palbociclib with the GPX4 inhibitors RSL3 and ML210 lead to further increase in lipid peroxidation