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Pyroptosis forms pores in the cell membrane via Gasdermin D, releasing pro-inflammatory factors and triggering local inflammation, which impairs endothelial function

Upon reaching the infection site, the overexpressed bacterial gelatinase degrades the gelatin core, triggering the controlled release of vancomycin and enabling site-specific antibacterial action [90]

At the core of spatial omics lies the integration of high-resolution imaging with molecular profiling, allowing the simultaneous detection of multiple biomolecular expressions within a single tissue section [286]

We have also analyzed sections of well-preserved surgically retrieved rare pancreatic biopsies from four living volunteers with recent-onset T1D, supplied by the Diabetes Virus Detection (DiViD) Study (Krogvold et al