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269 The benefits of TZDs in MASLD and fibrosis may be the increased adiponectin levels and the adiponectin-mediated effect on insulin sensitivity and hepatic fatty acid metabolism 270 and the downregulated fibrogenic factors and related pathways, inflammatory pathways like JAK/STAT and NF-B signaling pathways

Translation into people cannot be assumed

Severe Dehydration Signs of severe dehydration during pregnancy include dark urine, dizziness when standing, little to no urine production, and persistent thirst

This may be due to a rebound effect on appetite, since benzodiazepines have been shown to increase appetite in animals