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Nicotine has been shown to decrease TEER and disturb the BBB transport system, which leads to increased xenobiotic uptake (Manda et al., 2010

Some researchers hypothesize that DSIP may act as a hypothalamic peptide with broader physiological roles, similar to how growth hormone influences more than just tissue growth

Dihexa is a peptide variant of angiotensin IV that has been shown to significantly improve cognitive function in animal models of diseases such as Alzheimers

While hepatic metabolic dysfunction remodels immune cell behavior, activated immune cells can intensify or ameliorate hepatocyte injury and metabolic disturbances