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We adjusted observations that were generated in subpopulations, because it was the only significant bias covariate identified by the bias covariate selection algorithm (Supplementary Table 7)

PMID 33771566

[2] This settlement included payments to states, restrictions on advertisements, and free access to internal industry research, although some have criticized the settlement for shielding the industry from future lawsuits, granting a monopoly to the largest tobacco companies, creating "client states" dependent on settlement payments, and shifting the cost of cigarettes to individual smokers rather than companies

Unfortunately, the agency has been systematically neglected, leaving it struggling to fulfill its mission