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These small, inhaled particles emitted from vehicle exhaust, forest fires, coal-fired power plants and other industrial sources are thought to pass through the central airways and lodge in the more peripheral airways where LUADs typically form

Further studies are required to confirm these findings and to verify these hypotheses

Annu Rev Pharmacol Toxicol 49:5771 Beutel MW, Harmon TC, Novotny TE, Mock J, Gilmore ME, Hart SC, Traina S, Duttagupta S, Brooks A, Jerde CL, Hoh E, Van De Werfhorst LC, Butsic V, Wartenberg AC, Holden PA (2021) A review of environmental pollution from the use and disposal of cigarettes and electronic cigarettes: contaminants, sources, and impacts

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