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However, the neurobiological bases for these sex differences have eluded researchers, making it difficult to design gender-specific smoking cessation treatments

This is important given the unprecedented degree of aging of the world's human population, the fact that many people continue to smoke into old age 2 and the possibility that stopping early enough may help toward delaying dementia if it leads to a reversal of cortical thinning effects of smoking

Pharmacologic Management When behavioural counselling alone does not result in cessation, pharmacologic therapy may be considered as an adjunct to support quitting during pregnancy

Although direct causality remains contested within evidence-based tobacco policy discussions, these country-level experiences suggest that product differentiation , when combined with robust youth protection strategies and tobacco-control measures , may contribute to more significant and sustained reductions in smoking prevalence