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The covariates included demographic factors: age (1929 / 3039 / 4049 / 5059 / 6069 / 70), marital status (married / single or widow / divorced or separated), and educational level (middle school or below / high school / college or over)

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Users have full control over the amount of nicotine , or they can vape nicotine-free liquids

more than $600 billion in 2018 (combining health care spending and lost productivity)