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Experimental studies in animal models have demonstrated that disruption of opioid receptor-mediated neurotransmission leads to a reduction in social behaviors (Ragen et al

Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death

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By analyzing the FRET efficiency with FRET reporters placed at the C-termini of full-length GHR and C-terminal truncations, it was found, in general, that the dimeric-GHR ICDs are positioned at a greater distance apart, the further they are from the transmembrane domain (50)