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Rom J Morphol Embryol 61:1523

The transition should include a washout period of at least 1-2 weeks after the last cagrilintide injection, followed by starting the retatrutide titration from the beginning (1 mg weekly)

This is one reason why the standard protocol involves gradual dose escalation, and it is also why the first week on semaglutide can vary so much from person to person