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Cisplatin displays its capability to induce cellular senescence in various types of cancer, including ovarian cancer, lung cancer, hepatocellular carcinoma, nasopharyngeal cancer, and specific melanoma cell lines [53, 73,74,75,76]

4A), and the results revealed an upregulation of IRE1 (an ER stress marker), indicating ER stress activation, reduced p62 levels, and increased LC3BII levels within 012 h of PFOS treatment

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