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Supplementary file Table S1 outlines all 17 urine metabolites of VOCs analyzed in the study, including their parent compound and common names

The data shows the amount of a Hoffmann analytes found to be present in smoke extracted from a test smoking article under Health Canada Intensive conditions SS rod / KS filter (test) KS rod / KS filter (Ci) SS rod / SS filter (C2) KS rod / SS filter (C3) Total Normalised data Total Normalised data Total Normalised data Total Normalised dat Constituent amount amount amount amount () Tar Nicotine () Tar Nicotine () Tar Nicotine () Tar Nicoti Phenol 4-82 0.42 3-57 i9.o6 0.88 7-30 16.30 1.17 7.87 46.03 1.60 16.99 m-cresols 1.03 0.09 0.76 36 0.17 1.38 2.83 0.20 1-37 7-63 0.27 2.82 o-cresol 1.11 o.io 0.82 4-23 0.19 1.62 3-51 0.25 1.70 9.92 0.35 3-66 p-cresols 2.72 0.23 2.01 9-68 0.45 3-71 8.08 0.58 3-90 20.75 0.72 7.66 NFDPM 11-58 21.70 13-91 28.72 Nicotine 1-35 2.6l 2.07 2.71 CO 10.32 17.11 10.60 19-04 Water 6-35 11.65 9.90 i8.i6 TPM 19.28 35.96 25.88 49-59 Table 3: Hoffmann Analyte data at HCI conditions (HCI), namely a 55ml cigarette puff, lasting for 2 seconds, taken every 30 seconds, with filter ventilation blocked