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The more we can increase the diversity of tissues and number of samples from more people, the more we can learn. The study, The association of cigarette smoking with DNA methylation and gene expression in human tissue samples, was supported by the National Institutes of Health (grants U01 HG007601, R35 ES028379, R01 GM108711, and U24 CA210993)

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Worldwide, an estimated 1.14 billion people use tobacco

"Electronic Cigarettes What are the health effects of using e-cigarettes?" (PDF)