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There was this whole attempt to reduce tar and nicotine, says Tom Novotny, an epidemiologist at San Diego State University who was one of the first people to research the environmental impacts of cigarettes

Most people can take it, however it is not suitable for children under 18, women who are pregnant or breastfeeding and people with severe kidney problems

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Another in vitro study suggests that this may also be a specific effect of one of nicotines metabolites, called cotinine, as well as for other nicotine-like alkaloids such as anabasine