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Discussion Based on this occupational cohort with a long-term follow-up time, we explored the patterns of the exposure-response relationship between airborne arsenic exposure and CVD mortality and investigated the synergy effect of cigarette smoking

Chronic tobacco smoke exposure exacerbates hepatic inflammatory mediators and reactive oxygen species, precipitating fibro proliferative remodeling through hepatic stellate cell activation and matrix metalloproteinase dysregulation (Addissouky 2019

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