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g , Enrichment of EGFR p.L858R hotspot driver mutations in SBS4-positive tumours from never-smokers compared to smokers using multivariable logistic regressions considering clinical and epidemiological covariates, including age, sex, genetic ancestry, histology, and tumour purity ( n = 5 mutated non-smoker cases, n = 1 mutated smoker case, n = 51 non-smoker wild-type cases, n = 301 smoker wild-type tumours)

Given the substantial risks that these products pose to dental implant and bone grafting success, it is essential for clinicians to incorporate cessation programs into the treatment planning process