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Given our results, it is conceivable that this approach could also be highly effective outside a screening environment, such as post-traumatic stress clinics and among patients with cancer, cardiovascular disease or diabetes. Limitations of this study include that the population was predominately white and that the entire sample lacked CO (expired carbon monoxide) abstinence verification due to COVID restrictions after the study had begun, although overall results between sub-samples with and without verification were similar.

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