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Some of the best examples of research that had a significant impact throughout the negotiations included the following: The original epidemiologic studies linking smoking and lung cancer 29,30 Research on behavioral and pharmacological approaches to treating smoking 31 Research on the effects of second-hand smoke on health 20 Research linking tax increases to smoking decreases 18 The research-based evidence has been incorporated into model legislation for tobacco control, including manuals intended for the use of Convention delegates and their countries