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Yohannes Tesfaigzi, a senior scientist at the Lovelace Respiratory Research Institute in New Mexico, says for those with susceptible lungs, even very low levels of smoke exposure can result in an emergency room visit, and lasting long-term effects

12 A number of academic surveys have explored reasons for RYO use

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Although the mechanism by which smoking influences vWF release is not fully understood, it has been suggested that lipid peroxidase formed by O2 free-radicals and the effects of nicotine and CO2 contribute to the increase in vWF functional activity 28